Yes, the Hillman 16-gauge Copper Utility Wire (50160) can be used for jewelry making. Because it is high-purity copper, it is non-toxic. Keep in mind that it is hardware-grade and lacks the anti-tarnish coating found on "jewelry-grade" wire. It may oxidize and leave marks on the skin, and it is stiffer than "dead soft" craft wire. Many users apply a clear coat or sealant to their finished pieces to prevent oxidation and skin discoloration.